Expanesthetics Research Published in Anesthesia & Analgesia
A research letter published in Anesthesia & Analgesia reports the first peer-reviewed description of BTTE, a new inhaled anesthetic compound investigated by Expanesthetics researchers and collaborators at UC Davis. The study evaluated how the compound interacts with key anesthetic receptor systems and measured anesthetic and cardiovascular effects in a preclinical animal model. The investigators observed that BTTE produced general anesthesia and was associated with less hypotension compared with clinically used volatile anesthetics in this experimental setting.
"We're excited to share these initial findings and believe they provide a strong scientific foundation as we continue advancing our anesthetic discovery program."
Dr. Shane Austin, Chief Executive Officer
Recent Updates
Study Finds Post-Induction Hypotension Common in Older Patients Receiving Propofol
Coverage in Anesthesiology News reports that most patients age 65 and older experienced significant blood pressure reductions after induction with propofol, even at low doses. The findings highlight the ongoing hypotension challenge associated with currently used anesthetic agents.
Read moreDoctors Call for Balance Between Environmental Goals and Patient Needs
Several recent publications revisit how the environmental impact of inhaled anesthetics is measured and regulated. Authors note that commonly used carbon-equivalent comparisons may not fully reflect how short-lived anesthetic gases behave in the atmosphere, and emphasize balancing sustainability goals with clinical decision-making.
Read moreStudy Finds No Measurable Neurodevelopmental Harm After Brief Pediatric Inhaled Anesthesia
A randomized clinical trial reported in Anesthesiology found no significant cognitive, behavioral, or language differences in young children after a single short exposure to sevoflurane anesthesia. The findings add clinical data to an ongoing discussion about anesthetic safety in pediatric patients.
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